Please enable JavaScript.
Coggle requires JavaScript to display documents.
routine coagulation tests - Coggle Diagram
routine coagulation tests
PT
spin to achieve "platelet poor plasma"
unspun can be kept for 24hr at room temp
if spun test within 4 hrs
if cant be done seperate plasma and freeze
blue top tube-3.2%, 0.109M sodium citrate
9:1 ratio
if hematocrit>55% then use the equation 1.85X10^(-3)x(100-HCT)x V
no hemolysis
well mixed
21 guage needle would be best use (or biggest needle possible)
follow the order of draw carefully to not contaminate
screens the extrinsic and common pathway
test factors: VII, X, V, II, I
uses commercial thromboplastin reagent
phospholipid (TF)
calcium
thromboplastin
referance range: 10-13 sec
INR's referance range
Coumadin therapy: 2-3
critical value: >or= 5
It is used in the INR
((patients PT)/(mean PT of normal range))
this is the way to compare internationally
anticoagulant monitoring usually "bloodthiners"
aPTT (how it is different than PT)
contains activator to shorten clotting time (aPTT)
Has to be spun and analyzed within 4 hours
otherwise separate the plasma and freeze it
after thawing it must be tested within 1 hour
tests the intrinsic and common pathway
factors XII, XI, IX, X, V, II, I
usually ordered for heparin therapy and bleeding disorders before surgery
has negatively charged activator, a phospholipid, and calcium chloride
reference range: 30-40 secs (depends on time)
for heparin therapy it is 1.5-2.5 times the baseline PTT