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Blood 1 - Coggle Diagram

- - - - features
        
        lots granules (containing enzymes)
        
        nucleus 2/more lobes
        (polymorphonuclear)
      - NEUTROPHILS
        (60-70%)
        bacteria/fungal infection
        
        PHAGOCYTOSIS
        
        1. ACTIVATION
        
        of resting phagocytes
        
        by inflammatory mediators
        
        2. MOVEMENT
        
        of phagocytes
        
        to chemical attractants
        
        chemotaxis
        
        3. MARGINATION
        (movement towards vessel wall)
        
        ROLLING
        
        ADHESION (strong activation)
        
        4. DIAPEDESIS
        
        podocyte extensions squeeze between 2 adjacent endothelial cells
        
        neutrophils secrete collogenase + break down basement membrane
        
        5. RECOGNITION-ATTACHMENT
        
        attachment of phagocyte to pathogen
        
        6. INGESTION
        
        7. PATHOGEN KILLING & DEGRADATION
      - EOSINOPHILS
        (2-4%)
        allergic reaction/parasite
      - BASOPHILS
        (<1%)
        systemic inflammation/allergies
    - - features
        
        few/no granules
        
        nucleus NOT lobed
        
        mononuclear
      - LYMPHOCYTES
        (20-25%)
        smallest
      - MONOCYTES
        (3-8%)
        biggest