Please enable JavaScript.
Coggle requires JavaScript to display documents.
Gene Expression at the Molecular Level - Coggle Diagram
Gene Expression at
the Molecular Level
Central dogma
Transcription
site
promoter (begin)
terminator (ending)
3 stages
Elongation
Termination
Initiation
Translation
tRNA: Identical to
non-coding strand
(aka template)
genetic code
mRNA: Identical to
coding strand
(aka non-template)
degenerate code
Translation Requires
tRNA
Anticodon
Amino acid attachment site
translation factors
mRNA
genetic code to make a polypeptide
Ribosome
Eukaryotes
3 sites:
A, P & E sites
Prokaryotes
Stages of Translation
Elongation
amino acids are added to a growing polypeptide
Termination
recognized by release factors
Initiation
mRNA assembles with the ribosomal subunits
RNA Modification in Eukaryotes
Introns
– transcribed but not translated
Exons
– coding sequence found in mature mRNA
Cap + splice > poly A
Splicing
Alternative splicing
– produce different products
Capping
- mRNA to exit nucleus and bind
ribosome
Spliceosome
– removes introns precisely