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Musculoskeletal
system - Coggle Diagram
Musculoskeletal
system
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bone remodeling
REVERSAL : Mesenchymal stem cells appear along the burrow where they proliferate and differentiate into osteoblasts
FORMATION : They mature into osteoblasts at the surface of the burrow and release osteoid at the site to form a new matrix
RESORPTION : Osteoclasts dig out cavity in spongy bone, calcium released into blood and osteoclasts disappear
TERMINATION : After the new matrix is mineralized with calcium and phosphorous, it sites with resting lining cells until the next cycle
ACTIVATION : Pre-osteoclasts are binded to the remodeling sites and fuse to form multinucleated osteoclasts
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