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Exam 3 - Coggle Diagram
Exam 3
BLOOD: fluid connective tissue plasma, blood cells, platelets
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Blood Plasma
Fluid part of blood; 90% water; plasma proteins determines blood fluid volume; two-thirds of plasma protein are albumin
Other components: hormones, proteins, sugars, gases, amino acids
Plasma Portion: 50-60% volume; water 91-92%, proteins 7-8%, Ions sugar 1-2%
Cellular Portion: 40-50% volume; white blood cells, platelets, red blood cells
Cells
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Leukocytes: white blood cells: defend, remove dead & worn out cells
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Transport
Hemoglobin: transport oxygen; Heme; polypeptide chain (globin), Iron, Oxygen molecule
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New Blood Cells
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Complete Blood Count (CBC): # of red, white, and platelets per 1L of blood
Homeostasis
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erythropoietin (EPO): hormone, tells stem cells to produce more red blood cells
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Clotting
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- Vessel rupture: spasms contsrict 30m
- platelets arrive and clump (bandage/plug)
- sertotonin release extend spasms and attract platelets
- blood coagulates into gel and forms clot
Other
FIX: Factor X: protein, triggers production of thrombin
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Embolism
Embolus: clot circulation, heart, lungs, brain if clot closes organs blood supply (slur speech, droopy muscles eyelids, walk)
Stroke: embolus when blood flow blocked part of brain (area dies), mild
Wound healing
- form blood clot, 2. phagocytes clean up debris; 3. scab formation; 4. regen blood minimize blood loss and infection
Blood Disorders
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Anemias: red blood cell not deliver enough oxygen; iron-deficiency, pernicious (B12); aplastic (cancer)
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Environmental factors
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Toxemia: metabolic poison, kidneys couldn't remove toxic waste from blood, waste buildup prevent replacement of red blood cells & platelet function; blood cannot clot
IMMUNE SYSTEM
Notes
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Three defenses: phsyical barriers, innate immunity, adaptive immunity
Physical Barrier
Intact skin; linings of body cavities and tubes (chemical barriers), not part of immune system
Innate Immunity
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Innate immunity: preset response to infection (birth), white blood cells and blood proteins, general response
Adaptive immunity
triggered by innate, changes during lifetime. response tailored to particular attackers, white counterattack, 1w to develop
White Blood Cell Types
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Neutrophils: phagocytes follow trail to infected, inflamed, damaged tissue
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Barriers of Infection
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Lysozyme: eye; tears, saliva, gastric fluid protection
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Innate Immunity
Complement system: protein in circulation; activated upon contact w/antigens; coat/puncture pathogens
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Adaptive Defenses
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B Cells
Lymphocyte: effector, memory, plasma (make antibodies); antibodies to destroy (proteins)
T Cells
Cytotoxic, Helper; cells to destroy
Self v Non-self
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Non-self (Antigen): foreign, engulf/cuts, MHC mark for identification, display surface
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Immunology
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Allergens: pollen, food, drug, dust, venom, cosmetics; exposure = IgE generation; 2nd exposure = histamine release
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AIDS: kill patients; slow; drugs= protease inhibitor, suppress disease
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Respiratory System
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Respiration
Alveoli: thin, moist; gas exchange; Oxygen and carbon diffuse; surface area; larger surface area = efficiency; steep pressure = faster diffusion
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Cardiovascular Disorders
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Arrhythmias: irregular heart rhythm, fibrillation
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