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DIABETES MELLITUS - Coggle Diagram
DIABETES MELLITUS
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Classification of disease as per WHO, 1999
Type 1 diabetes mellitus
- insulin dependent diabetes IDDM
- 5 % of total diabetic patients
- deficient circulating level of insulin
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Type 2 diabetes mellitus
- non insulin dependent NIDDM
- most patients belong to this type
- insulin level normal or mildly elevated or slightly decreased
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glycated hemoglobin
Interpretation of values
- normal level less than 5.5 %
- good control by treatment - 6 %
- adequate control - 7 %
- inadequate control - 8 %
- very poor control - 9 %
Testing methods in lab
- HPLC assay
- antibody based latex enhanced immunoassay
- enzyme based enzyme assay
- ion exchange chromatography
Advantages of HbA1c estimation
- fasting sample not required
- low intraindividual variability
- not altered by acute factors
- reflects long term glucose control
- better index in predicting complications
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