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SEX - Coggle Diagram

- - - - stage 1: background information, build idea of person
      - stage 2: medical history
      - stage 3: information regarding medication
      - stage 4: first dose
      - stage 5: follow up
  - - - reversible
      - enables people to not go through puberty of gender they don't align with
    - - could lead to transition regret
      - bad side effects
- - - - genotype: XY
      - gonads
      - tract: wolffian: vans deferens + seminal ves
      - genitalia: scrotum + penis
    - - tract: mullerian: fallopian tubes + uterus
      - genitalia = clitoris, labia
      - genotype: XX
      - gonads: ovaries
- - - - puberty factors
        
        HPG axis
        
        hypothalamus releases GnRH, acts on pituitary gland which releases LH+FSH which act on the gonads
        
        spermatogenesis and testosterone secretion
        
        ovulatory phases + estrogen/progesterone secretion
        
        released every 1-2 hours on a circhoral rhythm
        
        kisspeptin: acts on receptors located on the GnRH producing neurons to activate them and commence puberty
        
        large amounts of leptin can activate this
      - development of 2' sex characteristics - facilitate mate attraction
      - gamete production starts - to enable contraception
    - - testosterone and fibriel addyi do not increase libido
        
        removing testes in rats and men, lowered libido, restored with testosterone but had no added effect after extra
        
        blood levels of TEST do not correlate to sexual vigour
        
        RODENTS removal of ovaries eliminates proceptve and receptive behaviours. proception reinstated with estradiol but not receptive
        
        human removal of ovaries has same affects as menopause. restored with oes/prog
        
        actual viagra
        
        sildenafil viagra
        
        mode of action: increase blood flow to penis
        
        side effects: facilitates erection but not libido
        
        mechanism of action: PDE5 inhibitor
        
        flibanserin Addyi
        
        extra testosterone will exert negative feedback on the HPG axis
      - to facilitate sexual activity
    - - to facilitate parent care of offspring
      - oxytocin
        
        a peptide hormone produced in HYPO.
        
        found various places in body
        
        mammary glands to promote lactatoin
        
        brain to stimulate the HPG axis and modulate limbic system
        
        on uterus to promote childbirth
        
        appears to suppress anxiety, fear and avoidance behaviours
        
        rises during sexual arousal and copulation in female > male
        
        administers increased feelings of trust and influences how males rate attractiveness of a female partner
- - - - genotype: XY
      - internal genitalia: male
      - tracts: male
      - external genotype: female
      - infertile
- - - - progesterone thickens cervical mucus
      - can sometimes project negative feedback too
    - - suppresses negative feedback on the HPG to suppress ovulation
      - also makes the uterus a not so comfy place for implantation to occur
  - - - females: 2' male sex characteristics
      - male: testicular atrophy, gynecomastia from armoatisation
      - intended affect: anabolic growth
      - side effects, premature death, liver strain, tumours, infertility