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Team Genesis (IVF) Implantation Concept Classification Tree - Coggle…
Team Genesis (IVF) Implantation Concept Classification Tree
Biological/In-Situ
endometrial receptivity array, determine when uterus is prime for embryo
uterus in a box (ex-vivo)
Chemical
chemical that improves blastocyst adherence to uterine wall
a virus that preps endometrial cells, modifies composition for optimal implantation
chemical adjuvant to speed up uterine thickening
chemically optimize the uterine microbiome for implantation
chemical stain to differentiate between good/bad sperm/embryos
induce epigenetic changes improve embryo quality
Digital
Apps
similar to a period tracker that can say best time for implantation
Microneedle patch & digital timer app with auto administration
simulation of endometrium and fallopian tubes to monitor blastocyst
patch with app connected to track uterus data
alerts patient to take certain supplement based on data from patch/implant
ROBOTIC :star:
inert nanoparticle that delivers embryo and adds hormones to uteral space
"PILL-LIKE" STRUCTURE TO ENTER AND FACILITATE IMPLANTATION :star:
blastocyst incubator that preps blastocyst in optimal conditions before implantation
catheter with digital monitoring and sensing of space
automate catheter implantation process
Hormonal pump (like an insulin analog)
Sensors
sensor for detecting hormones in the body
applying removable probe to detect healthy embryos
something to stick onto the cervix to measure HCG levels before detecting them in blood
IMAGING :star:
uterine imaging with surface-level attachment
imaging to differentiate b/w O, X embryos
digital screening for blastocyst quality
CAMERA/SCANNING DEVICE THAT CREATES 3D MODEL OF UTERINE WALL AND USES MACHINE LEARNING TO DETERMINE BEST LOCATION FOR IMPLANTATION :star:
imaging of embryos/eggs/sperm
Biochemical
genetic circuit to mass produce hormones
PEG-ylation of hormones for oral administration
solution to submerge blastocyst in that improves implantation rates
supplement you can add to food to balance hormones
localized patch
immune response inhibitor to ensure immune system doesn't attack blastocyst
hormone optimal uterus tampon
test to check chemical viability of embryo or sperm
genetic compatibility test between uterus lining and blastocyst
Pharmaceutical
Supplements
supplement you can add to food to balance hormones
tea bags that can balance out the hormones (can drink daily)
inhalable hormones delivered by inhaler
medicine to give to mother that preps her uterine before implantation for optimal results
Testing
at-home test to track ovulation or optimal implant times
test that creates the best diet for patient based on several factors that will help with overall uterus health
MATERIALS :star:
using more flexible biomaterial for catheter
augment catheter with scratcher
biomaterial that replicates uterine lining for ex vivo blastocyst growing
3D scaffolding to promote embryo implantation
hydrogel zipline to localize embryo implantation to optimal location
magnetic guide to ideal implantation zone
MICRON-SCALED OSMOTIC PUMP FOR SLOW, AUTOMATIC INTRAUTERINE PROGESTERONE RELEASE :star:
sperm solution filtering
Social
education of IVF clinicians to establish consistent implantation
educational programs that explain what to expect and how to manage emotional/physical challenges
incorporating input of registered dietitian nutritionists (RDNs) to promote healthier lifestyles and diets optimal for IVF
mental health assessments to identify individuals who need specialized support
financial counseling and guidance for IVF couples