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Suppositories 2 - Coggle Diagram

- - - - Natural, synthetic or modified natural prigins
      - Benefits: Physical or chemical incompatibilities of base with preservatives, emulsifiers or antioxidants
    - - Mixtures of TG with no sharp melting point so melting behavior is expressed as range of temperature at which fat starts to melt and at which it is completely melted
    - - Number of mg of KOH that would neutralize acetic acid consumed during acetylation of 1g of fat
      - Benefits
        
        Measure content of free hydroxyl groups in fatty base
        
        Determine monoglycerides & diglycerides content of base
    - - Determines time required for base to solidify when chilled in the mould
      - Refrigeration can be used to produce more efficient manufacturing process
    - - Number of KoH requirednto neutralize free acids and saponify 1g of fat
      - Benefits
        
        Indicate amount of glycerine in fat in addition to type of glycerine ( in. Mono, di or tri)
    - - No. If grams of Iodine that react with 100g of fat
      - Benefits
        
        Determine amount of unsaturation in FA
        
        When iodine increases, indicate decomposition of fats by moisture, acids, and oxygen that lead to rancidity of fat
    - - Amount of water in grams that can be incorporated in 100g of fat
        Can be increased by addition of SAA, monoglycerides or other emulsifiers
    - - Number of mg of KoH required to neutralize free acids in 1g of fat
      - Benefits
        
        Low acid value or complete absence of acid indicate good suppositories