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week 2 - Coggle Diagram

- - - - same amount of input will generate a larger response
    - - white matter made my meylin round an axon which is made my oligodendrocyte. makes conduction of action potential FASTER
    - - new cells replace old cells in the dentate gyrus
  - - - AMPA release Na
      - NMDA release Ca2+
        
        NMDA opens channel when 1. glutamate is bound and 2. AMPA has depolarised cell already
- - - - need motivation
        
        dopamine deficit mice do not learn to seek food if hungry. restoring dopamine restores motivation to engage in goal-directed behaviours
        
        2 dopamine systems
        
        mesolimbic pathway: VTA - NAc and on to limbic systems
        
        mesocortical pathway: VTA - PFC and onto cortical systems
        
        VTA = responds to sensory
        
        PFC = conducts planning of decision to approach the reward
        
        NAc = acquiring the behaviour if there is a reward
        
        Schulz study: monkey in front of 2 lever. if press right lever after visual cue get juice. measure midbrain dopamine activity. initially dopamine spikes after juice but then goes to spiking at the cue pre juice
- - - - damaged semantic and episodic
        
        only episodic is usually associated with hippocampal damage and semantic memory associated with temporal but also must be other places