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inflammation definition, cell tissue/adaptation and cell injury, Healing…

- - - - persistent infection
        
        hypersensitivity diseases
        
        Prolonged exposure to toxic agents
        
        endogenous
        
        exogenous (eg the suture material)
    - - what is it
      - why does it form
        
        specific interactions eg mycobacteria, fungi and syphilis
        
        materials that resist digestion (exogenous and endogenous)
        
        specific chemicals (eg beryllium)
        
        drugs eg hepatic granulomas due to sulphonamides causing crystaluria
        
        Unknown eg Chron disease, Sarcoidosis and Wegner granulomatosis
      - granuloma vs granilation tissue
  - - - resolution
      - fibrosis
    - - serous
        
        fibrinous
        
        suppurative
        
        ulcer
- - - - eg myocardial infarction
    - - eg thyroid hyperplasia causing goitre
        
        hyperthyroidism: graves disease
        
        hypothyroidism: chronic hashimoto's disease, iodine deficiency
- - - - ischaemic
      - chemical
      - toxic (eg from bacterial toxins)
- - - - due to iscahemia/infarction
        
        causes ghost outlines of the cell --> cell structure without nucleus
    - - cheese like necrosis
        
        associated with TB
        
        for TB use the Ziehl-Neelsen (ZH stain)
    - - can be due to infarction too
        
        necrosis in the brain due to post stroke
    - - caused by twisting of vessels
        
        that's why it usually occurs in organs with more than one blood supply
    - - pus formation
        
        pus contains neutrophils
        
        indicative of a pyretic bacteria
    - - death of tissue due to lack of blood flow
- - - - fibroblast growth factor
      - transforming growth factor
- - - - myocardial infarction
      - brain infarction
    - - labile
      - stable
      - permernant
  - - - granulation tissue formation