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Antimicrobial Chemotherapy - Coggle Diagram

- - - - Prevent bacteria synthesis of folic acid
        humans use preformed folate
    - - Acts on bacterial cell wall
        Abscent in humans
  - - - Active only against limited range of bacteria
        eg benzylpenicillin
    - - Active against wide range of bacteria
        eg amoxiclav
  - - - Kills Bacteria
      - Examples
        
        Beta-Lactam
        
        Cephlosporins
        
        Monobactams
        
        Carbapenems
        
        Glycopeptides
    - - Stops bacteria from multiplying
      - Examples
        
        Tetracyclines
        
        Sulfonamides
        
        Macrolides
        
        Lincosamides
  - - - • Beta-lactam antibiotics (penicillins, cephalosporins)
      - • Glycopeptides e.g. vancomycin
    - - • Quinolones e.g. ciprofloxacin
      - • Metronidazole
      - • Trimethoprim
      - • Rifampicin
    - - Aminoglycosides e.g. gentamicin
      - • Macrolides e.g. erythromycin
      - • Tetracyclines e.g. doxycycline
- - - - Alteration in target site
      - Change to structure of cell wall
- - - - Lab results
      - Antibiotic regiment
  - - - Check culture and susceptibility results
    - - Guidlines determined by
        
        Bacteria likely to cause the infx
        
        Which antiobiotics are likely to be effective against
      - Varies between regions / hospitals
        Patterns of infx and antibiotic resistance are diffeent in different populations