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TREATMENT OF GLAUCOMA - Coggle Diagram

- - - - Stinging
      - Blurred vision
      - Burning
      - Tearing
      - Dryness
    - - Gastrointestinal disorders
      - Headache, Dizziness
      - Bitter taste (25%)
      - Depression
      - Fatigue
- - - - Ocular pruritus
      - Ocular dryness
      - Growth Ocular burning of eyelashes
      - Visual disturbance
      - Conjuctival hyperemia
    - - Cataract
      - Decreased visual acuity
      - Increase thickening, elongation & growth of eyelashes
      - Abnormal vision
      - Increase pigmentation of iris
    - - Increase in brown pigmentation of the iris
      - Conjuctival hyperemia
      - Burning & stinging
      - Eye pain & Dry eye
      - Blurred vision
- - - - Timolol
      - Levobunolol
    - - Betaxolol
  - - - Hypotension
      - Increase plasma cholesterol level
      - Headache, Impotent
      - Insomnia
    - - Blurred vision
      - Burning/ stinging on instillation
      - Itching
      - Ocular irritation
- - - - Apraclonidine
    - - Brimonidine
  - - - Pupil dilation (for Apraclonidine)
      - Allergy (up to 26% for Brimonidine, up to 36% for Apraclonidine)
      - Lid elevation
      - Uveitis +/- Allergic conjunctivitis +/- IOP increase (Brimonidine)
      - Rebound hyperemia
    - - Fatigue
      - Dizziness
      - Headaches
      - Decrease in systolic blood pressure
      - Dry mouth
- - - - Produce miosis & contracts the ciliary muscle
      - Causing increased tension on scleral spur & opening of trabecular meshwork spaces to facilitate outflow of aqueous humor
      - Acts through direct stimulation of muscarinic receptors & smooth muscle including the iris & secretory glands
      - Outflow resistance is reduced, lowering intraocular pressure (IOP)
    - - It mimics the effects of Ach
      - Causing miosis and a spasm of accommodation in which the ciliary muscle of the eye remains in a constant state of contraction
      - Acts through muscarinic and nicotinic receptor