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CLINICAL APPROACH TO FATIGUE - Coggle Diagram
CLINICAL APPROACH TO FATIGUE
HISTORY
Alcohol consumption
Drugs/Medication history
-Cocaine, Antidepressants
-Stimulants
-Antibiotics
-Marijuana
-Antihistamines
-Muscle Relaxants
-Nicotine
-Opioids etc.
Social History: Occupation? Shift work?
Associated symptoms
Psychological
-Lack of motivation
-Irritability
-Anxiety
-Suicidal thoughts
-Cynicism, doubt and pessimism
Loss of sleep
Somatic
-Low
energy
-Headache
-Heaviness in arms
-Dizziness
-Sore muscles/Joint pain/Back pain
Weakness
Hot/Cold spells
Duration
Onset
Assessment of severity: How has it impacted the quality of life and daily
routine
RED FLAGS IN HISTORY
-Fever
-Unintentional weight loss
-Loss of appetite
-Lymphadenopathy
-Poor concentration
-Muscle and Joint pain
-Focal Neurological symptoms
-New onset fatigue
-Chronic lower back pain with an unknown cause
-Abnormal Bleeding
-Shortness of breath
-Chronic cough
-Genitourinary symptoms
EVALUATION OF FATIGUE
PHYSICAL EXAMINATION
Thyroid Examination
Abdominal Examination
Skin Pigmentation
weight, pallor, jaundice loss of appetite
Vital Signs
INVESTIGATION
Blood Glucose Levels
Thyroid Function tests
CBC, CRP, ESR, RFT, LFT,
Serum Electrolytes
Creatine Kinase
Urine Analysis
CXR
CAUSES OF FATIGUE
PITFALLS
Pregnancy
Food intolerance
Menopause Syndrome
NON-ORGANIC CAUSES
OCCUPATIONAL
Workload and Environmental factors
(exposure of various chemicals, air and noise pollution)
Mental/Muscular Exertion
(history of increased sweating and increased heart rate on minimum work)
IDIOPATHIC
Fibromyalgia
(widespread musculoskeletal pain with sleep, memory and mood issues)
Chronic Fatigue Syndrome with impaired memory memory,lymphadenopathy, joint pain and headaches
Chronic fatigue syndrome(hx of more than 6 months) With impaired memory, Lymphadenopathy, Joint pain and Headaches
PSYCHOGENIC
Malnutrition/Drug Addiction
(chronic condition featured as continued use of drugs despite negative consequences) ( poor weight gain and poor growth)
Anxiety + Depression
(younger patients with somatization disorder, cognitive impairment and panic attacks)
Sleep disorders
(suggestive history of stress, changes in schedule and environment)
ORGANIC CAUSES
PHARMACOLOGIC
Antihypertensives, Antidepressants, Analgesics, Opioids, Sedatives, Drug abuse, Drug withdrawals
INFECTIOUS
Parasitic Disease
(present with diarrhea, fever and vomiting)
Endocarditis
(chest pain with fatigue and fever and swelling of feet, legs and belly)
HIV/Infectious mononucleosis
Hepatitis
(jaundice, fever fatigue and abdominal pain)
Tuberculosis
(malaise, fever weight loss and anorexia)
NEOPLASTIC
Malignant Disease
ENDOCRINE/METABOLIC
Hypercalcemia, Hypomagnesaemia, Hypokalaemia
(presents with bone pain, renal colic, dyspnea, and exercise intolerance)
Diabetes Mellitus
(polyuria, polyphagia, and polydipsia with lethargy and nausea)
Hypo/Hyperthyroidism
(presents with anxiety, tremors, cold and heat intolerance, weight gain and loss)
Pituitary and Adrenal Insufficiency
(hormonal imbalances, mood changes and hot flashes)
Liver and Renal Failure
(yellow eyes and skin, tender abdomen, changes in mental state, fluid retention, swelling of legs, ankle and feet)
CHRONIC DISEASES
Neurological
Parkinson's Disease
(bradykinesia, dizziness, dystonia, postural instability)
Somatization Disorder
(signs of severe physical illness without any medical causes)
Stroke/Cerebral Ischemia
(sudden numbness and weakness of face,arm and leg with trouble movement)
Inflammatory/Autoimmune
Polymyalgia, Systematic Lupus Erythematosus
(skin rashes, fever Raynaud phenomenon)
Rheumatoid Arrthritis
(stiffness and swelling in one or more joints with fever fatigue and weight loss)
Multiple Sclerosis , Myasthenia Gravis
(difficult swallowing, numbness of arm, impaired speech)
Cardiopulmonary
Peripheral Vascular Disease
(intermittent pain and claudication of muscle esp in legs muscles)
Atypical Angina
(chest pain radiate to jaw and left arm)
COPD
(sob with wheezing and chest tightness, chronic cough with mucus production)
Congestive Cardiac Failure, Cardiomyopathy, Cardiac Arrhythmia