Fever,unintentional weight loss.sensory loss,loss of appetite,lymphadenopathy,poor concentration,muscle and joint pain,focal neurological symptoms
New onset fatigue in previously well old patient
Chronic Low back pain in the absence of known factors
Abnormal bleeding.
SOB, chronic cough.
Genitourinary symptoms(i.e urinary retention, loss of sensation around the back passage,incontinence)