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Cystic Fibrosis (CF) - Coggle Diagram

- - - - Pancreatic insufficiency
        
        Foul-smelling, bulky stools
        
        Malabsorption of nutrients (e.g., fat-soluble vitamins)
      - Malnutrition
        
        Failure to thrive
        
        Pancreatic enzyme deficiency
      - Treatment
        
        Pancreatic enzyme replacement
        
        High-calorie, high-fat diet
        
        Fat-soluble vitamin supplements
  - - - Excessive mucus production
        
        Frequent lung infections (e.g., Pseudomonas aeruginosa)
        
        Progressive lung damage
        
        Alterations in Function
        
        Airway obstruction
        
        Reduced lung function
        
        Bronchiectasis
        
        Respiratory distress
        
        Chronic cough
      - Chest physiotherapy
        
        Bronchodilators
        
        Inhaled antibiotics
        
        Lung transplantation
  - - - Dehydration
      - Electrolyte imbalances
      - Growth failure
      - Digital clubbing (fingers and toes)
      - Chronic sinusitis
      - Treatment
        
        Reproductive system issues (infertility)
        
        Liver and gallbladder complications
        
        Sweat gland dysfunction
        
        Antibiotics for infections
        
        Mucolytic agents
        
        Anti-inflammatory drugs
        
        Gene Targeted: CFTR modulators (e.g., Ivacaftor)
        Emerging gene therapies