Female Reproductive
Mammary gland
Ovary
Areolar & Nipple
Oviduct
Corpus luteum
Ovarian follicle
Vagina
Uterus
บุด้วย Tunica albuginea is dense irregular CNT
location: cortex and surround by stromal cell
Type
Growing follicle
Mature follicle
Primordial follicle
surround by one layer of squamous cell
Unilaminar primary follicle
Multilaminar primary follicle
one layer of cuboidal follicular cell
Large nucleus
several layer of follicular (granulosa) cells
Secondary follicle
Stage become atretic
single layer surround by primary Oocyte is know a corona radiata
medium size of antrum
large antrum
large Oocyte
เห็น corona radiata ชัดเจน
Oocyte Meiotic Division
Ovulation
Second: begin and stop at metaphase
Second meiotic : complete after fertilization
First : occurs just prior to ovulation
Theca interna
Theca externa
cuboidal
steroid producing cell feature
compose of CNT and stroma cell
flat cell
Theca lutein cell
Granulosa lutein cell
produce estrogen, progesterone, androgen
secrete progesterone
corpus albicans
large one form after pregnancy and smaller ones after ewch ovulation
on surface corpus albicans is visible as a scar
corpus luteum degenerate is invaded by fibrobladts
serosa : CNT line by simple squamous epith.
Lamina propria : loose CNT
site of fertilization
cells in oviduct
muscular tube
Inner circular layer
outer longitudinal layer
Ciliated cell
Peg cell : produce water tubal fluid
3 regions
Body
Fundus
Cervix
Myometrium
Adventitia/Seosa
Endometrium
Myometrium
Adventitia/Serosa
Endometrium
Thickest layer
4 poorly defined layers
Smooth muscle separated by CNT
Inner&outer layers are mostly longitudinal
Middle layers are highly vascularized&mostly circularly smooth muscle
Stratum vasculare
Estrogen dependent
Thicken during pregnancy
Smooth muscle cell atrophies and some begin to apoptosis when absent os estrogen
Simple columnar with ciliated epithelium
Secretory columnar cells in epthelium
Lamina propria
Dense irregular CNT
Vessels
Simple tubular glands have not ciliated cells
2 Zone
Functional layer
Basal layer
Sloughed off during menstruation
Replaced during each menstrual cycle
Coiled helical arteries that originate from arcuate arteries in stratum vasculare
Retained after menstruation whose glands epith. And CNT element regenerate functional layer
Short straight arteries which originate from arcuate arteries in stratum vasculare
Menstrual Cycle
Estrogen and progesterone changes
Average cycle is 28 days
3 main phases
Menstrual phase
Proliferative(follicular) phase
Secretory(luteal) phase
Days 1-4
Days 5-14
Simple columnar epith.&tubular glands
CNT cells proliferate in lamina propria
Coiled arteries grow into regenerated lamina propria
Functional layer thicker and fully restored at day 14
Days 15-28
Corpus luteum forms&produces progesterone
Glands become highly coiled branched and begin secrete
Coiled arteries attain full development
If fertilization doesn’t take place
Corpus luteum stops secreting hormones
Endometrial cells die and functional layer sloughed off
Vessels distal to constrictions are shed with the
functional layer causing some bleeding
Mucous secreting simple columnar epithelium
cervix in upper vagina has stratified squamous
nonkeratinized epithelium
mostly dense connective tissue and many elastic fibers and a few smooth muscle cells in lamina propria
Stratified squamous non-keratinized epithelium
Estrogen stimulates to synthesize glycogen
No glands but inclement of fluid during sexual arousal
compund tubuloacinar glands similar to apocrine sweat glands
secrete apocrine mechanism (lipids) and exocytosis (proteins)
Acini has many plasma cells and lymphocytes, sources of milk immunoglobins
Interlobular ducts have simple cuboidal epithelium
Resting stage
Active stage
Alveolar
Nipple
Circular highly pigmented skin
Sweat&sebaceous glands and areolar glands of Montgomery
Stratified squamous keratinized epithelium
Dense collagenous CNT with abundant elastic fibers