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Female Reproductive, mens cycle, primordial, secondary, tritary,…

- - - - produce estrogen, progesterone, androgen
    - - secrete progesterone
- - - - Unilaminar primary follicle
        
        one layer of cuboidal follicular cell
        
        Large nucleus
      - Multilaminar primary follicle
        
        several layer of follicular (granulosa) cells
      - Secondary follicle
        
        Stage become atretic
        
        single layer surround by primary Oocyte is know a corona radiata
        
        medium size of antrum
    - - large antrum
      - large Oocyte
      - เห็น corona radiata ชัดเจน
    - - surround by one layer of squamous cell
- - - - Myometrium
        
        Simple columnar with ciliated epithelium
        
        Secretory columnar cells in epthelium
        
        Lamina propria
        
        Dense irregular CNT
        
        Vessels
        
        Simple tubular glands have not ciliated cells
        
        2 Zone
        
        Functional layer
        
        Sloughed off during menstruation
        
        Replaced during each menstrual cycle
        
        Coiled helical arteries that originate from arcuate arteries in stratum vasculare
        
        Basal layer
        
        Retained after menstruation whose glands epith. And CNT element regenerate functional layer
        
        Short straight arteries which originate from arcuate arteries in stratum vasculare
      - Adventitia/Seosa
      - Endometrium
        
        Thickest layer
        
        4 poorly defined layers
        
        Smooth muscle separated by CNT
        
        Inner&outer layers are mostly longitudinal
        
        Middle layers are highly vascularized&mostly circularly smooth muscle
        
        Thicken during pregnancy
        
        Stratum vasculare
        
        Estrogen dependent
        
        Smooth muscle cell atrophies and some begin to apoptosis when absent os estrogen
    - - Myometrium
      - Adventitia/Serosa
      - Endometrium
    - - Mucous secreting simple columnar epithelium
      - cervix in upper vagina has stratified squamous
        nonkeratinized epithelium
      - mostly dense connective tissue and many elastic fibers and a few smooth muscle cells in lamina propria
  - - - Menstrual phase
        
        Days 1-4
      - Proliferative(follicular) phase
        
        Days 5-14
        
        Simple columnar epith.&tubular glands
        
        CNT cells proliferate in lamina propria
        
        Coiled arteries grow into regenerated lamina propria
        
        Functional layer thicker and fully restored at day 14
      - Secretory(luteal) phase
        
        Days 15-28
        
        Corpus luteum forms&produces progesterone
        
        Glands become highly coiled branched and begin secrete
        
        Coiled arteries attain full development
    - - Corpus luteum stops secreting hormones
      - Endometrial cells die and functional layer sloughed off
      - Vessels distal to constrictions are shed with the
        functional layer causing some bleeding