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Mesenchymal stem cell-released oncolytic virus, Snapshot summary:, MSC…
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MSC carrying OV's have shown some success in various model trials however there are many challenges that still present themselves as a safe and effective method for cancer treatment. A number of viruses have been selected to become the basis for these OVs and the immune system still proves itself to be a formidable barrier.
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Darestani, Nadia Ghasemi. Et al. Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment. 2023. Cell Communication and Signaling. 21:43. https://doi.org/10.1186/s12964-022-01012-0