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Filariasis - Coggle Diagram

- - - - Quantity of Accumulating Adult Worms in Lymphatic System
      - Degree of Host Immune Response
      - Duration & Level of Exposure to Infective Insect Bites
    - - Inflammatory Phase
        
        Antigens Elicit Inflammatory Responses
        
        Body Proteins & Secretions - Cause Irritation --> Lymphangitis & Lymphadenitis
    - - Obstruction
        
        Block Lymphatic Vessels & LN
        
        Infiltration w/ Macrophages, Eosinophils, Lymphocytes, Plasma Cells
        
        Thickened Vessel Wall & Narrowed Lumen
        
        Thrombus, Granuloma Formation, Fibrosis & Permanent Lymphatic Obstruction
      - Elephantiasis
        
        Skin Becomes Coarse & Wrinkled, Dark, Thick, Pebbly
        
        Common after 25 Years of Infection
        
        Chronic Lymphatic Obstruction & Excessive Fibrosis of Lymphatic Vessels