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Characteristics of Drosophila Melanogaster - Coggle Diagram
Characteristics of Drosophila Melanogaster
1-Short generation size
Rapid reproduction
High reproductive rate
Quick experimentation
Genetic diversity
Mutation research
Evolutionary experiments
Crossbreeding
Mutant screening
8-Small size and easy maintenance
Easy to house in small containers
Housing in vials or small plastic containers
Ventilated lids to prevent mold
Culture medium (cornmeal, agar, yeast)
Easy to maintain at lab setting (25c room temperature)
Inexpensive and readily available
Anesthetize with CO2 for sorting and experiments
Gentle manipulation with fine brushes or aspirators
6-Genetic tools
Genetics (punnet squares, monohybrid and dihybrid crosses phenotypic ratio)
Genome editing (CRISPR/CAS9 used for targeted gene knockout, gene tagging)
Balancer chromosomes (Suppress recombination, maintain heterozygosity)
Genetic screens (forward and reverse genetics, Enhancer and Suppressor Screens)
RNAi (gene knockdown, dsRNA or shRNA constructs, RNAi libraries)
3-Well characterized genome
Provides the complete DNA sequence of the genome of DM
Identification and annotation of genes, regulatory elements, and non-coding regions.
Identification of protein-coding genes and their functions
Discovery of non-coding RNAs (microRNAs, lncRNAs)
Characterization of regions that control gene expression
Comparison of the Drosophila genome with other species to identify conserved elements.
Analyzing genome diversity in different Drosophila populations
4-Conservation of biological processes
Understanding evolutionary relationships
Insights into human biology
Developmental Processes (embryogenesis, metamorphosis)
Physiological Functions (Circadian rhythms, immune response)
Genetic Pathways (Wnt, Hedgehog and Notch signaling)
2-Complex genetic traits
Multiple genes contribute to the phenotype (gene A,B,C etc.)
Regions of chromosomes associated with complex traits (QTL 1, 2, 3)
Wing Size (Multiple genes affect the size of Drosophila wings)
Eye Color (A polygenic trait influenced by several genes)
Some traits are temperature-sensitive
7-Developmental biology
Genes and Signaling Pathways
Morphological Development
Regulation and Function
Experimental Techniques
5-Evolutionary studies
Genes involved in evolution
Mutation accumulation
Genetic drift
Genetic drift
Long-term evolution experiments
9-Neuroscience and behavior
Disease Modeling (e.g., Parkinson's)
Understanding Human Behavior
Cross-Species Comparisons
Translating Findings to Humans
Behavioral Studies
10-Education and training
Advancing Scientific Knowledge
Workshops and Conferences
Importance of Drosophila Training