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Cardiovascular system drugs, Renin-Angiotensin-Aldosterone System (RAAS) -…

- - - - Mechanism: Cardiac glycoside that inhibit sodium-potassium (Na+/K+) pump in cardiac cells that lead to increase calcium level in intracellular. Enhance myocardial contractility and slow down electrical conduction of AV node.
      - Prescribe: Atrial fibrillation/flutter, hear failure.
      - Side effect: CNS and GI toxicities, anorexia (loss appetite), visual disturbance.
    - - Mechanism: Stabilize cell membranes and inhibit calcium influx into cardiac cells. Also modulating potassium channel and Na+/K+ pump activity.
      - Prescribe: Arrhythmias, hypomagnesemia, Torsades de Pointes, prolong QT interval.
    - - Mechanism: A natural occurring nucleoside act as potent vasodilator and slow down hear electrical conduction through AV node that interrupting pathway of tachycardia.
      - Prescribe: Supraventricular tachycardia.
- - - - Vasoconstriction
      - Stimulation of Aldosterone Release
      - Thirst and Antidiuretic Hormone (ADH) Release
      - Stimulation of Sodium Reabsorption
      - Promotion of Cardiac Hypertrophy