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Stomach Adenocarcinoma - Coggle Diagram

- - - - Environmental
      - Male
      - Old Age (55 Years Old)
      - APC Gene Mutation
      - Hematogenous Spread
      - Gland Formation
      - Gastric Atrophy, Intestinal Metaplasia
    - - Familial
      - Blood Type A
      - Female
      - Poorly Differentiated Gland
      - Transmural/Lymphatic Spread
      - Low E-Cadherin (CDH1 Gene Mutation)
- - - - Bulky, Exophytic Mass
      - Apical Mucin Vacuoles
      - Abundant Mucin
    - - Signet Ring Cell (Nucleus at Periphery)
      - Desmoplastic Reaction
      - Leather Bottle Appearance (Linitis Plastica)
      - Thickened Wall + Loss of Rugal Folds