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Primary GORD, Conditions with increased acid production, Secondary GORD -…

- - - - Seal of lower oesophageal sphincter has reduced structural support
        
        Excessive/prolonged transient lower oesophageal sphincter relaxation
        
        Hydrochloric acid in stomach pushed up
        
        Increased intra-abdominal pressure or positional changes
        
        Heartburn
        
        Acid regurgitation
        
        Aspiration of acid into larynx > lungs
        
        1 more item...
        
        Repeated oesophagus damage
        
        Scarring leads to oesophageal narrowing
        
        1 more item...
        
        Metaplasia
        
        2 more items...
- - - - Vagus nerve stimulates lower oesophageal sphincter relaxation