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Jaundice - Coggle Diagram
Jaundice
Laboratory Tests
Coombs Test
Detects Presence of Antibodies on RBCs
Reticulocyte Count
Bone Marrow Production of RBC
Total Serum Bili (TCB)
Direct Bilirubin
Water Soluble
Indirect Bilirubin
Fat Soluable
Liver Function Tests
Liver Injury of Inflammation
ALT
AST
Cholestasis or Liver Dysfunction
GGT
ALP
Blood Culture
R/O Sepsis
Type and Screen
CBC
Risk Factors
Preterm Birth
Immature Liver
ABO/RH Incompatibility
Rh - Mother
O Mother and A, B, or AB Baby
Infection
Sepsis
Increased Cell Breakdown
Exclusive Breastfeeding
Inadequate Intake
Dehydration leading to decrease bilirubin excretion
Sibling History of Jaundice
Ethnicity
Asian
Mediterranean
Cephalohematoma
Infant of a Diabetic Mother
Visible Signs of Bruising
Causes
Physiological
Causes
Increased breakdown of fetal red blood cells after birth
Immature liver function
Most Common Type
Peaks 3rd to 5th day
Resolves Over 2 Weeks
Pathological
Hemolytic
Blood Group Incompatibilites
ABO Incompatabilities
Mother Blood type O
Baby Blood Type A, B, or AB
Rh incompatibility
Mother is Rh-negative
Baby is Rh-positive
Other Blood Disorders
G6PD
Hereditary Spherocytosis
Pyruvate Kinase
Congenital Erythropoietic Porphyria
RBC Structural Abnormalities
Sherocytosis
Elliptocytosis
Breastfeeding Jaundice
Early Onset
Breastmil Jaundice
Late Onset
Liver Dysfunction (Pathological)
Causes
Infections
Metabolic disorders
Inborn errors of metabolism
Galactosemia
Tyrosinemia
Disorders of Conjugation
Gilbert Syndrome
Crigler-NajjarType I-II
Pyloric Stenosis
Hypothyroidism
Physical Examination
Yellow Sclera
Yellow Skin tone
Hemolytic Jaundice
Pallor d/t reduced red blood cell count
Hepatosplenomegaly
Anemia
Hemoglobinuria
Hepatomegaly
Treatments
Phototherapy
Exchange Transfusion
Intravenous Immunoglobulin (IVIG)
Complications/Outcomes
Kernicterus
Acute Bilirubin Encephalopathy
Neurodevelopmental Impairment
Prevention
Early and Frequent Breastfeeding
Monitoring High Risk Infants
Bilirubin Nomogram
Bili Tool
Rh Immunoglobulin Administration
Rh - Mother
Second Pregnancy