Please enable JavaScript.
Coggle requires JavaScript to display documents.
Haemopathology, Haemolytic uremic syndrome (HUS), Thrombotic…
Haemopathology
Secondary hemostasis disorders
Intrinsic pathway
Hemophilia B
Factor 9
Hemophilia A
Factor 8
Hemophilia C
Factor 11
APTT increased
extrinsic pathway
Factor 7 deficiency
PT increased
shared pathway
Deficiency/inhibition of vitamin K-dependent coagulation factors
II
VII
X
II
APTT/PT increased
Signs
spontaneous hemarthrosis
ecchymosis (secondary hemostasis)
Spontaneous hemorrhage in areas susceptible to trauma
patechiae (primary hemostasis)
Primary hemostasis disorders
Destruction
Thrombocytopenia
Dysfunction
VWD
GP1 deficiency
Thrombotic microangiopathy
Dilution
Blood transfusion
Sequestration
hypersplenism
Anemia
Macrocytic
Nonmegaloblastic
Diamond-blackfan
alcoholism
liver disease
Megaloblastic
Folate deficiency
B12 deficiency
Normocytic
Non-hemolytic (retic <2%)
Early IDA
Aplastic anemia
CKD
Hemolytic
(retic > 2%)
Extravascular hemolysis
Intravascular hemolysis
Microcytic
HGB defects
Defective heme synthesis
Iron deficiency
lead poisoning
Sideroblastic anemia
Anemia of chronic illness
Defective globin chain
Thalassemia
Disorders of fibrinolysis
Hereditary hypercoagulability
(hypofibrinolysis)
Factor V Leiden
Antithrombin III deficiency
Protein C deficiency
Protein S deficiency
Hyperfibrinolysis
DIC
Haemolytic uremic syndrome (HUS)
Thrombotic thrombocytopenic purpura (TTP)