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Pernicious Anemia Macrocytic/normochromic - Coggle Diagram
Pernicious Anemia Macrocytic/normochromic
causes
Intrinsic factor deficiency, resulting in malabsorption of B12
Signs and Symptoms
Weakness
glossitis
palpations
dizziness
anorexia
paresthesia
loss of vibratory sense
loss of fine motor control
(+) Romberg/Babinski
Labs
Low: Hgb, Hct, RBC's, B12
High: MCV
Diagnostics: Anti-IF, anti parietal cell antibody, & Schilling tests
Treatment
B12 (cyanocobalamin) 100mcg IM daily x1 week
Monthly admin for maintance