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Altered Hormonal and Metabolic Regulation - Coggle Diagram
Altered Hormonal and Metabolic Regulation
Syndrome of Inappropriate Anti-directive Hormone
Excessive production and release of ADH
Diagnostic
Lab finding
Less than 280 Hyopotoniaity
less than 135 Hyponatremia
Absence of renal, adrenal, thyroid
Treatment
removing cause of SIADH, Water restriction, IV Saline
Manifestation
decrease of concentration urine output
Anorexia, nausea, vomiting, weakness
Hyperthyroidism
State of excessive thyroid Hormone
Diagnostic
Family history of autoimmune disease, thyroid disease, iodine deficit, physical examine measurement of TSH levels
Treatment
Decrease in thyroid hormone, gland destruction, oral thyroid hormone replacement therapy
Manifestation
Enlargement of thyroid gland, excessive metabolic rate, and weight, heat intolerance, tachycardia
Diabetes Insipidus
insufficient ADH = Inability for body to concentrate or retain water
Diagnostic
Pt history, physical examination, lab showing serum solute concentration
Treatment
Hydration, desmopression
Manifestation
Large Volume urine output, excessive thirst, stroke or death
Cushing Syndrom
Prolong elevated levels of either endogenous or exogenous glucorticoids
Diagnostics
24hr urine collection = increase cortisol excretion
Treatment
Removal of excessive hormone production, surgery or radiation needed to remove tumors, corticosteroid medication
Manifestation
Metabolic Alteration, excessive circulating glucose, behavioral changes, imbalance stress responses, obesity
Inflammatory and immune responses
Addison Disease
Lack of CRH or ACTH from adrenal cortex
Treatment
Isotonic IV fluid replacement and Sodium or potassium replacement, Antibiotic if bacteria is present
Diagnostic
Lab analysis of electrolyte levels, hyponatrenta and hyperkalemia, serum corticosteroid levels
Manifestation
Skin melanocytes, weakness, weight loss, vomiting, dehydration
Hypothyroidism
Deficient thyroid hormone
Diagnostic
Sensitive TSH Assay, free T4, total T4, T3 uptake, thyroid autoantibodies, and antithyroglobulin test
Treatment
Replacing hormones with normalization of TSH, T4, T3 levels, lifelong thyroid hormone replacement therapy
Manifestion
Fatigue, cold intolerance, weakness, weight gain, dry skin, constipation, lethargic, impaired memory, myxedema