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Opioid Analgesics, Few Opioid Analgesics, Opioid Antagonists - Coggle…

- - - - Apnoea of Neonate - When opioids are given for labor analgesia
  - - - Uses - 3 - Codeine, Dextromethrphan – used as antitussive
        C/I productive cough - ↑accumulation of secretions → atelectasis
    - - Tolerance develops on repeated dosing
  - - - Tolerance does not develop to miosis – addicts have pin-point pupils
    - - Except Pethidine/ Pentazocine
    - - Max with IV Fentanyl & analogues
        Neuromuscular blockers to treat, while preserving analgesia
  - - - Tolerance does NOT develop
        Opioid induced constipation – laxatives, methylnaltrexone
      - Uses - 3 - Loperamide, Diphenoxylate - used as antidiarrheal
        C/I infective diarrheoa
    - - Due to histamine release
    - - NOT suited for ureteric colic