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PERIODONTAL DISEASE - Coggle Diagram

- - - - biological phenotype
        
        inflammatory biomakers
        
        cellular & molecular response
      - genetic epigenetic
        
        age
        
        gender
      - personal level
        
        biofilm
        
        smoking
        
        obesity
  - - - bacteria
      - host immune factors
      - acquired risk factors
      - environmental risk factors
  - - - stress
      - genetics
      - diabetes
      - smoking
  - - - initial
      - early
      - established
      - advanced
  - - - Inflammation
      - Destruction
      - microbial dysbiosis
    - - smoking
      - systemic disease
      - genetics
  - - - biofilm & specific bacteria
  - - - disease causing potential
        
        synergy
        
        antagonism
    - - trigger dysbiosis
      - cause self destruction
- - - - RESORPTION OF ALVEOLAR BONE