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Pathology pt.2 - Coggle Diagram

- - - - Activation of phospholipase and proelastase
        
        Degrades fat and damages elastic fibers
      - Activates prekalikinin
        
        Coagulation and inflammation
  - - - Leads to blocked ducts
        
        Juices back up and increase pressure leading to distended ducts
    - - Leading to immune response
        
        Neutrophils release ROS and proteases
- - - - Dark urine due to Urobilinogen
      - High UCB overwhelms liver's conjugating ability
    - - Low UGT activity and therefore inc. UCB
- - - - Constipation, straining and low-fiber diet
      - Arise where the vasa recta traverse the muscularis propria; sigmoid colon is most common location