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Male Hormonal drugs, Female Hormonal drugs - Coggle Diagram
Male Hormonal drugs
DEPO-Testosterone
Mechanism of action
Testosterone and its androgenic metabolite, dihydrotestosterone, exert biological effects directly through binding to the androgen receptor and indirectly through aromatization of testosterone to estradiol, which allows action via binding to the estrogen receptor
Indications
indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone.
Nursing consideration
Contraindications
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Patients with serious cardiac, hepatic or renal disease
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Side effects
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Oily skin, hair loss, and acne may occur.
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References
Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 5/16/2022
Medically reviewed by Darren Hein, PharmD — By The Healthline Editorial Team — Updated on August 23, 2018
Female Hormonal drugs
Clomiphene
Mechanism of action
Clomiphene is a selective estrogen receptor modulator (SERM). It selectively binds to estrogen receptors in the hypothalamus, ovary, endometrium cervix and produces estrogenic and anti-estrogenic effects. It also acts as a partial estrogen agonist in the hypothalamus resulting in an estrogenic negative feedback inhibition, thus increasing gonadotropins.[
Indications
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Medication indicated to treat anovulatory or oligo-ovulatory infertility to induce ovulation for patients desiring to conceive.
Nursing considerations
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Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
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References
Von Hofe J, Bates GW. Ovulation induction. Obstet Gynecol Clin North Am. 2015 Mar;42(1):27-37
Megan Brady Shannon, MD Fellow in Female Pelvic Medicine and Reconstructive Surgery, Loyola University HospitalUpdated: Jul 27, 2021.
Contraceptive implant
Mechanism of action
contraceptive implant works to prevent pregnancy by releasing a low, steady dose of the hormone progestin. Contraceptive implants are a long-term birth control method.
Indications
indicated for women for the prevention of pregnancy.Is a long-acting (up to 3 years), reversible, contraceptive method.
Nursing considerations
Contraindications
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Liver disease, including severe cirrhosis or liver tumors.
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Side effects
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Higher risk of noncancerous, or benign, ovarian cysts.
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Route of administration
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The implant releases a low, steady dose of the hormone progestin.
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Vagifem
Mechanism of action
Is a nuclear hormone, meaning it acts on receptors present inside the cell, that can activate or deactivate transcription in the nucleus. It interacts with a target cell receptor within the cytoplasm of the cell.
Indications
Vagifem is an estrogen (estradiol) indicated for the treatment of atrophic vaginitis due to menopause.
Nursing considerations
Contraindications
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Known, suspected, or history of breast cancer
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