Episodes of apnea and hypopnea associated with symptoms such as excessive daytime and cardiovascular morbidity and mortality

1.- During sleep, there is decreased tonic activity of the laryngeal, supraglottic, oropharyngeal, nasopharyngeal, and lingual musculature, which results in dynamic collapse with respiration.

2.- This decreased upper airway tonic activity results in a dynamic decrease in the caliber of the upper airway and therefore increased resistance to airflow.

3.- The effects of this dynamic collapse can range from mild collapse without significant changes to respiration and no effect on oxygenation or arousal to complete airway obstruction, decreased oxygenation, and frequent arousals throughout sleep

A hoarse sound that occurs when air flows past relaxed tissues in the throat , causing the tissues to vibrate during breathing

The tendency to fall asleep involuntarily in inappropriate situations during the day warrants clinical attention

In North America found prevalence rates for an AHI of more than five episodes per hour of 24 percent in men and 9 percent in women, and for OSAHS with an index greater than five episodes per hour plus excessive sleepiness of 4 percent in men and 2 percent in women.

Which obesity is considered to be an important determinant. Ethnic differences in prevalence have also been found after adjustment for other risk factors. Little is known about the incidence in resource-poor countries.