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effect of recreational drugs on transmission - Coggle Diagram
effect of recreational drugs on transmission
terminology
up regulation- additional receptors due to increased levels of hormones
down regulation- decrease in the amount of receptors, decreasing response to stimulus
agonist- a drug that has same effect as naturally produced NT
antagonist- prevents effects of naturally produced NTs
alcohol
inhibits neural transmission by increasing GABA
makes you feel: happy, sociable and more confident
depressant effect on nervous system
too much alcohol can mean slurred speech, blurred vision, loss of balance/ co-ordination
binge drinking can lead to: injuries from falls, accidents or assaults. long term effects can include: damage to the brain, body and organs (spef liver)
heroine
reduces GABA; leads to overactivity of dopaminergic neurotransmission in reward pathways of the brain
negative effects: drowsy, dry mouth, slower heart rate and breathing, may feel sick and vomit if you are not used to effect
makes you feel happy, euphoric, sleepy and relaxed
amphetamine
makes you alert, energised, chatty, agitated
increases levels of noradrenaline and dopamine in synapse by reversing reuptake process
excess dopamine in synapse
decreased appetite and insomnia
cocaine
blocks uptake of dopamine in presynaptic neuron so more remains in synapse
increases alertness and causes euphoria, risk taking, excitement, panicky/ anxious, confidence
regular use can make you feel depressed and run down
can have: heart attack, panic attack, or stroke if you take too much cocaine