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Bioinorganic CH4208 - Coggle Diagram
Bioinorganic CH4208
Describe the ways in which spectroscopic and kinetic techniques, and synthetic model compounds can be used to study metalloprotein mechanisms; apply this knowledge to unseen problems.
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Discuss the role played by platinum compounds as anti-cancer therapies and explain the fundamental coordination chemistry underpinning their mode of action; critically assess the design features of potential Pt-based anti-cancer agents.
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Describe how specific metals are used to carry out activation of small molecules such as H2, CO, O2, and N2, and discuss the importance of both metal coordination and macromolecular structure in tuning the chemistry of metal centres in proteins; be able to rationalise protein function based on metal coordination.
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Describe the occurrence and function of metals in biological systems including the transport and storage of oxygen and electron transport processes.
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Apply the knowledge gained in this module to conclude whether a given metal complex/ligand system is suitable for a particular therapeutic application.