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Renal Tubular Function - Coggle Diagram
Renal Tubular Function
Fractional Excretion
Amount that is excreted relative to amount passing through Glomerulus
Major Functions of Parts of Nephron
Proximal Tubule
67% of Na Reabsorbed
67% of H2O reabsorbed
Organic Solute Secretion
Thin Descending Limb
Permeable to Water reabsorption
Thick Limb
25% of Na is reabsorbed
Passive Transport
Is water impermeable but NaCl is reabsorbed
Site of Loop Diuretics
Distal Convoluted Tubule
5% of Na reabsorbed
Thiazide Diuretics blocks NaCl
Cortical Collecting Duct
3% of Na reabsorption
Na Reabsorption/K secretion
ADH affects water permeability
Major Site of action of Aldosterone
Increases Na-K-ATPase in basolateral
Increase expression of ENaC in apical membrane
Increase channel activating protease
Types of Transport Systems
Passive Transport
Proteins to Aid in the travel down their concentration gradient/electrochemical gradient
Active Transports
Solutes moved against their concentration gradient via energy dependent or active transport proteins
Paracellular Transport
Movement between tight junctions of cells
Water Movement
Moves through Specialized Channels: Aquaporins
