Coggle requires JavaScript to display documents.
depression, mania or mixtures (spectrum)
Improvement Response > 50% reduction symptoms Remission Recovery > after 6-12 months Worsening Relapse Recurrence
depletion --> synapse maintenance fails --> dendrites lost and neuronal death --> neuroprogression of depression
wakefulness is not promoted in the morning, such patients tend to sleep latertrouble to fall asleep at nightfeelings of sleepiness during the day
hyper-reactive to induce sadnesshypo-reactive to induce happiness
frequent and early awakenings
decrease in delta sleep increase in surface sleep REM sleep disturbance
not all patients improveepisode of mania
day : accumulation intensityasleep : impulses encoding irrelevant memory return to normal levelno asleep : accumulation keep going --> optimal stage for plasticity
effective treaatment for depression slower than total sleep deprivation