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ANEMIA - Coggle Diagram
ANEMIA
Hemoglobin
The protein contained in red blood cells that is responsible for delivery of oxygen to the tissues
Structure
Hemoglobin has two parts
o Protein part (globin)
o Non-protein part (Heme=iron + porphyrin)
Heme synthesis
Types of Hb
Alfa (α) chain
synthesized throughout pre- and post-natal life
Gamma (γ) chain
synthesized from 2nd trimester and starts disappearing after birth
Epsilon (ε) & zeta (ζ) chains
synthesized during first trimester only.
Delta (δ) chain is
synthesized throughout adult life at low levels
Beta (ß) chain
mainly synthesized after birth.
Iron transport
Preventative methods for hematological disorders
Iron deficiency anemia
Iron supplements
Diet(green vegies/salmon)
Megaloblastic anemia
diet in folic acid & vitB12
Pernicious anemia
vitB12 shots
Sideroblastic anemia
Prevent lead poisoning
Complications of anemia
Heart Problems
Issues With Pregnancy
Weakened Immune System
Impaired Development
Hematopoiesis & Histology of Hematopoietic and Lymphoid Organs
Histology of hematopoiesis
Histology of lymphoid organs
RBC Types, Indices, and Formation (EPO)
RBC Indices
Red blood cell (RBC) indices are part of the complete blood count (CBC) test
Role of EPO in RBC Formation
A hormone called erythropoietin (EPO) spurs red blood cell production. Hormones are chemical messengers that coordinate essential body functions. Your kidneys secrete most of your body’s EPO.
Anemia
types
Etiology
Dietary lack
Impaired absorption
Increased requirement
Pathogenesis
Examination of lymph nodes and history for hematological disorders
Examination
History for hematological disorders
Interpret the results of blood test
Blood test results components
complete blood count
white blood cells (WBCs)
Red blood cells (RBCs)
Platelets
metabolic panel
lipid panel
Differential white blood cell count
The lab tests the five main components of white blood cells and their proportion to each other
