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Equine hyperadrenocorticism - Coggle Diagram
Equine hyperadrenocorticism
Which hormone is not at the correct level?
Adrenocorticotropic hormone (ACTH)
Comes from
the pituitary gland
what does it do?
Controls the production of the hormone Cortisol.
how is homeostasis usually maintained
Maintained by the glucocorticoid feedback mechanism.
Clinical Signs
Weight loss
Polydipsia
Increased Coat length
Polyuria
increased sweating
Laminitis
failure to shed winter coat
lethargy
weight loss
pot-bellied appearance
How to Diagnose?
Measurement the adrenocorticotropic (ACTH) hormone
Combined lead to diagnosis
Perform a thyrotropin releasing hormone (TRH) test
Treatment
outcomes
without
Depending on the clinical signs
manage clinical signs such as
laminitis
secondary infections
and excessive hair growth
Modify diet
With
Not a cure : needs to maintain a regular administration of medication
65% - 85% efficacy rate
Tablet called Prascend (pergolide)
routine blood work to monitor ACHT levels
Who does this effect?
middle age to older horses.
average age?
19 years
references
equine hyperadrenocorticism. (2022).
https://www.rvc.ac.uk
. Retrieved March 28, 2023, from
https://www.rvc.ac.uk/equine-vet/information-and-advice/fact-files/cushings-disease#panel-key-points
Dacvim, H. C. S. I. D. P. (2020, April 27). Pathogenesis and diagnosis of equine Cushing’s disease (Proceedings). DVM 360.
https://www.dvm360.com/view/pathogenesis-and-diagnosis-equine-cushings-disease-proceedings-0
Colville, T. P., & Bassert, J. M. (2015b). Clinical Anatomy and Physiology for Veterinary Technicians. Elsevier Health Sciences.
