Please enable JavaScript.
Coggle requires JavaScript to display documents.
Acute Inflammation, A rapid & local inflammatory response to tissue…
Acute Inflammation
-
Causes
Infections: bacterial, viral, parasitic, fungal
-
Physical agents: burns, corrosives
Tissue necrosis (death) - e.g. via ischemia, myocardial infarction
-
Hypersensitivity reactions - e.g. allergies, asthma
-
-
Inflammatory cells
-
Eosinophils
-
-
Enzymes (peroxidases, collagenases)
-
-
-
-
-
-
-
Chemical mediators
-
Vasoactive Amines
Histamine
-
Source: Mast cells, basophils, platelets
Stored in mast cell granules & released by mast cell degranulation in response to a variety of stimuli - physical injury, binding of antibodies to mast cells (allergic)
Ab & complement products bind to specific receptors on mast cells & trigger signalling pathways that induce rapid degranulation
-
-
-
-
