serious complicated skin and skin structures infections and intra-abdominal infections, broad spectrum including MRSA, VRSA streptococci, enterococci, anaerobes, rickettsia, chlamydia, legionella and rapidly growing mycobacteria. ineffective against Proteus and Pseudomonas. Tigecycline is administered intravenously. It is mainly excreted in bile, so does not require dose adjustment in renal failure
