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Non-Narcotic Analgesic - Coggle Diagram

- - - - Salicylate
      - Irreversible COX acetylation (prevents formation of prostaglandin H2)
    - - Not anti-inflammatory
      - Weak COX1/2 inhibitor, potent COX3 inhibitor
- - - - Production of Prostaglandins
        
        Prostaglandins bind to PGE2 receptor
        
        Vasodilation and Oedema
        
        Peripheral Sensation + Enhanced depolarisation of 2ndary sensory neurons