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Lymphatic/Immune System - Coggle Diagram
Lymphatic/Immune System
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Antigens and antibodies
Antigens: substances that can mobilize adaptive defenses and provoke an immune response,targets of all adaptive immune responses and can be a complete antigen or hapten (incomplete),contain antigentic determinants and can be a self-antigen.
Antibodies: also called Immunoglobulins (Igs); are proteins secreted by plasma cells,are capable of binding specifically with antigen detected by B cells and Overall T- or Y-shaped antibody monomer consists of four looping polypeptide
chains linked by disulfide bonds, Two identical heavy (H) chains and Two identical light (L) chains.
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Purpose and examples of First, Second and Third line of defense
The first line of defense consists of skin, mucous membranes,and secretions of skin skin and membranes. The first line of defence includes physical and chemical barriers that are always ready and prepared to defend the body from infection.
Ex: Surface barriers breached by nicks or cuts trigger the internal second line of defense that
protects deeper tissues
The second line of defence are phagocytic leukocytes, antimicrobial protiens, inflammatory response, and fever. This is the immune system.The second line supports management to help ensure risk and controls are effectively managed
Ex:Many second-line cells have pattern recognition receptors that recognize and bind tightly to structures on microbes, disarming them before they do harm
. The third line of defense consists of lymphocytes, antibodies, and memory cells. The third line defense aims at eliminating specific pathogens that have been encountered by the immune system previously. Instead of being restricted to the site of infection, the adaptive immune response occurs throughout the body.
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