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CANCER Undifferentiated and uncontrolled cell division, 3. How it…
CANCER Undifferentiated and uncontrolled cell division
1.TYPES
Sarcoma (Cancer of connective tissues)
Leukemia (Cancer of Blood Forming tissue)
Carcinoma (common cancer; Epithelial Tissue)
Lymphoma/myeloma (Cancer of Immune system)
BREAT CANCER
Risk factors
Family history of cancer
Hormonal factors and
Gender
Radiation Exposure
Age
Life style factors
Mutations in the BRCA1 and BRCA2 genes
Sign/Symptoms
multiple lumps or thickening in the breast or underarm area
Unexplained weight loss
change in the size or shape of the breast
Fatigue
Nipple discharge
Breast pain or tenderness
Skin changes on the breast, such as dimpling, redness, or scaling
Treatment
Lumpectomy/Mastectomy
Hormone therapy/targeted therapy
Radiation/Chemotherapy
Types
Invasive Lobular Carcinoma (ILC): milk-producing glands (lobules) of the breast. ILC accounts for about 10-15%
Triple Negative Breast Cancer (TNBC): Aggressive one
Invasive Ductal Carcinoma (IDC); Milk Duct; accounting for 80% of all breast cancer cases
HER2-positive Breast Cancer: aggressive one but treatable
Ductal Carcinoma In Situ (DCIS); Benign; Breast milk duct
P53; Tumor suppressor
DNA Repair
Senescent cells
Cell Cycle arrest
Apoptosis
2. CASUES
Excess Alcohol
Smoking
Radiation
Exposure to certain chemical
Genetic Mutation
3. How it propagate
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