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Biomed BMET1960, Cohort Studies and Patient confidentiality - Coggle…

- - - - Engineers Australia Code
  - - - Demonstration of moral character over consequence
      - Motivated by outstanding virtues
    - - Decisions over consequence
      - Uphold rights of all parties
    - - Pros and Cons
      - Judgement based on outcome
      - Maximise happiness, minimise suffering
      - Limitations: May impact individual for overall good.
    - - Decision making over consequence
      - Framework or existing policy to guide
      - Limitation: Detached from scenario
    - - Limitation: Compromises others
      - Focus on self and personal
        gain; intrinsically unethical
      - Intertwined with personal ethics
- - - - Transmission: Radiation sources OUTSIDE body passing through
      - X-rays
    - - magnetic waves
  - - - radioisotopes of 1 gamma ray in all directions
    - - Tracer Principle: Biological pathway of labeled (radioactive) molecules can be traced
      - Uses positron emitting technology(antiparticle)
  - - - Structural changes: Surgical implants to restrict movement
      - Temporal Changes: Faster machinery
      - Sedation
    - - Gating
- - - - Bone Cells
        
        Osteoclasts: Remove
        
        Osteocytes: Mechanireceptors
        
        Osteoblasts: Build
        
        Osteoporosis
    - - Syonovial Joints
        
        Osteoarthritis
  - - - Myofibrils (thick filament is attracted to thin filament, allowing for contraction
      - Shortening of Sarcomeres containing Myofibrils
      - Triggered by voluntary nerve impulse releasing calcium opening binding sites
- - - - Integration with materials to replicate function or encourage regrowth
  - - - Tailorable
      - Difficult to sterilise
    - - Easy to sterilise
      - Corrosive
    - - Corrosive Resitant
      - Compromised mechanics
- - - - Florescent tags
    - - Targeted drug delivery systems
      - Controlled drug delivery (therapeutic window)
      - Drug releasing stations e.g Doxorubicin
      - Targeted cell killing : Photothermal Therapy
        
        Gold nanoparticles as conductors
  - - - Altering surface e.g Polyethylene glycol limits opsonisation
      - Susceptible to immune response Mononuclear Phagocyte System
      - Protein Coronas
    - - Ligand Receptors: Engineering NPs to 'lock'
      - Leaky Vasculature around tumors
      - Functionalizing/Conjugating
- - - - Smart toys to stimulate brain and physical development
      - Stem cells in foetus' to aid development
      - Soft exoskeletons
        
        soft robotic outer pumped with air to assist in standing and sitting development (under 2yrs)
      - Implants
        
        Brain computer interface technology
        
        Electrodes in spine to aid muscular reflexes
      - Telehealth
      - Goal of assistive Technologies
        
        To meet frame work of wholistic life. To give them tools to improve quality of life not change their identity of life.
        
        Involve people with disabilities in design process
    - - Impacts speech, physical development etc.
  - - - Infared visible light to measure body composition
      - In response to undernutrition and causes of obeisity.
    - - Analyse current leaks that impact facial muscle spasms
- - - - Controlled Flow
        
        Brownian Motion: Thermal energy
        
        Speed as a determinate for rate of diffusion
  - - - Increase amount of results
  - - - Pre-clinical testing applications
      - Drug testing applications
- - - - Circadian Rythm
        
        Body Clock
        
        Melatonin
        
        Photoreceptors
      - Sleep-Wake Homeostasis
        
        Sleep Drive Based of awake time
      - REM & NREM
      - Sleep Efficiency = time asleep/ time in bed
- - - - Separation of layers of imaging
      - Longitudinal or diagonally
      - Creating digital surface
- - - - Doesn't adress issue, interrupts messaging to brain
- - - - I - self declared
      - II - Evaluation/Audits
      - III - Full clinical testing
  - - - Management Responsibility
      - Documentation and Controll
      - Customer supplied product
      - Product traceability
      - Controll e.g. calibration
      - Control of non-conforming products
      - Recording of handling, storage etc.
      - Essentially know what you're building
- - - - Interfering flow of electricity to brain
    - - Electrodes deep in brain to restore motor function.
    - - Cochlear electrode array implanted
        
        Increase word and Speech perception
      - Bone Conduction implants
      - Future of gene therapy to treat deafness