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ubiquitination - Coggle Diagram
ubiquitination
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Proteasome inhibitors
how to inhibit proteasome: the first proteasome inhibitor was simple peptide aldehyde which binds to chymotrypsin-like site
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Proteasome
large protein complex, main type is 26S. consists of 20S core and 19S regulatory particles.
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MONOubiquitination doesn't lead to degradation, but regulates activity