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Semi-Conservative DNA replication, Mechanism - Coggle Diagram
Semi-Conservative DNA replication
Messleson-Stahl
Experiment
How it proved semi conservative
Watson-Crick model of DNA
Suggested that their model seemed to suggest itself a method of replication (i.e. semiconservative?)
Actual Mechanism of replication
Polymerase complex
Okazaki Fragments and primers
initiation of replication inside cells
Okasaki experiment?
Other models of replication that were disproved by messleson-stahl.
Diagrams
Diagram per slide?
Watson-crick model
Test tube from Messleson-stahl
Nucleotide demonstrating Pol action and polarity
Timeline for conclusion slide
Mechanism
Polymerase
Proof reading domain
incorporation
polarity and proof reading
Okazaki fragments and the leading vs lagging strand
DNA primase
DNA helicase and single-stranded binding proteins
Topoisomerases and torsional stress
Repair after replication
DNA ligase