Please enable JavaScript.

Coggle requires JavaScript to display documents.

Autonomic Nervous System, Examples of Adrenergic Agents, shock, Agonist …

- - - - Secretes epinephrine & nonrepinephrine
      - Bladder relaxes :forbidden: :toilet:
      - Activates fight or flight
      - Inhibits activity of intestines
      - Pupils dilate :arrow_up: :eye:
      - Inhibits activity of stomach :forbidden: :hamburger:
      - Inhibits Salivation :forbidden::tongue:
      - Airways relax 🫁
      - Heart rate increased :arrow_up::heartbeat:
      - Liver releases glucose :candy:
  - - - Acetylcholine
    - - Norepinephrine
        
        α1 = blood vessels/veins
        β1 = heart
        β2 = lungs
    - - Epinephrine
      - Norepinephrine
    - - beta
        
        inhibit + relax
        
        β1 = heart is stimulated, increases heart rate and strength :blue_heart:
        
        β2 = lungs, eyes, smooth muscles = relax, vasodilation :cloud: :eyes: :muscle::skin-tone-5:
      - alpha
        
        excites
        
        α2 = blocks release of NE
        
        α1 = vasoconstriction of blood vessels
  - - - α- AND β- Blocking Agents
        
        suffix: -alol
        
        Selective α-blocker and nonselective β-blocker
        
        Treatment of hypertension and produces fall in BP without tachycardia
      - β-Adrenergic Blocking Agents
        
        Blocks β-receptors in adrenergic nervous system
        
        Suffix: -olol
        
        Specific vs. Nonspecific
        
        Specific
        More activity on heart & blood vessels
        i.e. atenolol
        
        Nonspecific
        More activity on lungs
        i.e. propranolol
      - α-Adrenergic Blocking Agents
        
        Competively inhibits the vasoconstricting effects of adrenergic agents
        
        Examples of α-adrenergic Agents
        
        Tolazoline
        Prazosin
        Terazosin
        Doxazosin
  - - - Asthma
        Anaphylaxis
        Hypotension
        As a vasoconstrictor
        Hemostasis (control bleeding)
        Nasal congestion
        Tx of cardiac arrest + shock
        Overactive bladder
        To stimulate the CNS
    - - Uncontrolled HBP
        Angina
        Hyperthyroidism
- - - - Antagonist
      - Similar to adrenergic effect
      - P-(blocks PANS)
      - Act as an anticholinergenic agent
    - - Acts as a cholinergic agent
      - Agonist
      - Similar to anti-adrenergic efect
      - P+ (stim PANS)
    - - Glaucoma treatment (elevated intraocular pressure)
      - Myasthenia gravis (muscle weakness) 💪
      - Xerostomia treatment
    - - Bronchial asthma
      - Hyperthyroidism
      - Gastrointestinal/urinary tract obstruction
      - Severe cardiac disease
      - Peptic ulcer
      - Myasthenia gravis
  - - - Acetylcholine
    - - Acetylcholine
        
        Glands
        Heart
        Smooth muscles
      - Short