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HEPATITIS B - Coggle Diagram
HEPATITIS B
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INVESTIGATIONS
serological markers (HBsAg, HBeAg, anti-Hbs, anti-Hbc, anti Hbe
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DEFINITION
Hepatitis B is an infection of the liver caused by the hepatitis B virus. The infection can be acute (short and severe) or chronic (long term).
PATHOPHYSIOLOGY
Hepatitis B virus (HBV) spreads through blood or bodily fluids, with oral-fecal transmission being rare. Liver damage is largely immune-mediated, involving T cell-induced lysis of infected hepatocytes, though HBV can also cause direct injury. In post-transplant patients, fibrosing cholestatic hepatitis suggests HBV pathogenicity independent of immune response.
TREATMENT
Care for acute hepatitis B should focus on making the person comfortable. They should eat a healthy diet and drink plenty of liquids to prevent dehydration from vomiting and diarrhoea.
Chronic hepatitis B infection can be treated with oral medicines, including tenofovir or entecavir.