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Vitamin B Complex, VITAMIN B1 (Thiamine - Anti-Beri Beri), ملخص - Coggle…

- - - - inflammation and fissure of the corners of the mouth.
    - - inflamed painful tongue.
  - - - Flavin mononucleotide (FMN)
      - Flavin adenine dinucleotide (FAD)
  - - - FMN
      - FAD
- - - - Nicotinamide adenine dinucleotide phosphate (NADP)
        
        N.B.
        
        Nicotinic acid is formed inside the body from tryptophan amino acid.
      - Nicotinamide adenine dinucleotide (NAD)
  - - - which affects mainly farmers using
        maize flour
        (deficient in tryptophan and nicotinic acid).
      - 3Ds
        
        diarrhea
        
        dementia
        
        4-death :red_cross:
        
        dermatitis
- - - - which acts as an acyl-carrier in many reactions, e.g. acetyl-CoA, succinyl-CoA.
- - - - PLP acts as co-enzyme for amino acid absorption and transport.
      - PLP acts as co-enzyme in many enzymes in amino acid metabolism.
      - PLP acts as co-enzyme in heme synthesis.
  - - - due to impaired heme synthesis.
    - - vitamin B6 was found to be effective in treatment of nausea, anorexia and vomiting during pregnancy
- - - - conversion of pyruvate to oxaloacetate by pyruvate carboxylase.
- - - - Promotes red blood cell formation.
      - Prevents birth defects of spine and brain.
- - - - Anemia, leucopenia, and thrombocytopenia
      - Degeneration of peripheral nerves which may cause numbness, tingling in fingers and toes.
- - - - peripheral neuritis, confusion, muscle weakness.
    - - anorexia, nausea, and vomiting.
    - - cardiac enlargement, edema (wet Beri Beri), and may be heart failure.
    - - Since vitamin B1 is used in carbohydrate metabolism, people who suffer starvation may have vitamin B1 deficiency, thus feeding them with carbohydrates (IV glucose) without supplementing them with vitamin B1 may cause Beri-Beri to appear.