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Drugs acting on skin, Anti-seborrheics, Agents for Acne, Factors Affecting…
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Agents for Acne
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Erythromycin (3% cream, gel, or lotion)
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Retinoids: Includes tretinoin, adapalene, and isotretinoin for keratinocyte normalization.
Salicylic Acid: Keratolytic, clears blocked pores.
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Overview
The skin is a dynamic organ providing protection, thermoregulation, and vitamin D synthesis.
Conditions like acne, rosacea, infections, and psoriasis are treated using various topical and systemic drugs.
Topical Preparations
include sprays, lotions, gels, creams, and ointments.
Factors affecting choice: lesion type, drug potency, skin integrity, and site of application.
Agents for Rosacea
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Doxycycline, Metronidazole, Oxymetazoline: Control rosacea symptoms.
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Agents for Psoriasis
Retinoids (Tazarotene, Acitretin): Normalize keratinocyte differentiation.
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Biologic Agents: TNF-α blockers like adalimumab, infliximab, and etanercept.
Coal Tar, Salicylic Acid, Methotrexate: Other systemic and topical options.
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Demelanizing agents
Hydroquinone, Monobenzone, and Azelaic acid
Melanizing agents
Psoralen, Methoxsalen, and Trioxsalen
Sunscreens
- Chemical Sunscreens: Para-aminobenzoic acid (PABA), Oxybenzone, Octyl methoxy cinnamate
- Physical Sunscreens: Petroleum jelly (heavy), Titanium dioxide, Zinc oxide, Calamine
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